Publications of the Institute of Medical Physics and Biophysics in 2019

Authors:Banchenko S, Arumughan A, Petrović S, Schwefel D, Wanker EE, Roske Y, Heinemann U

Title:Common Mode of Remodeling AAA ATPases p97/CDC48 by Their Disassembling Cofactors ASPL/PUX1

Journal:Structure Year:2019; Volume:27Issue:(12):Pages:1830-1841.e3. doi: 10.1016/j.str.2019.10.001. Epub 2019 Oct 21.

Authors:Hill J, Enbody ED, Pettersson ME, Sprehn CG, Bekkevold D, Folkvord A, Laikre L, Kleinau G, Scheerer P, Andersson L

Title:Recurrent convergent evolution at amino acid residue 261 in fish rhodopsin

Journal:Proc Natl Acad Sci U S A Year:2019; Volume:116Issue:(37):Pages:18473-18478. doi: 10.1073/pnas.1908332116.

Authors:Fudim R, Szczepek M, Vierock J, Vogt A, Schmidt A, Kleinau G, Fischer P, Bartl F, Scheerer P, Hegemann P

Title:Design of a light-gated proton channel based on the crystal structure of Coccomyxa rhodopsin

Journal:Science Signal Year:2019; Volume:12Issue:(537):Pages:pii: eaav4203. doi: 10.1126/scisignal.aav4203.

Authors:Brosig A, Fuchs J, Ipek F, Kroon C, Schrötter S, Vadhvani M, Polyzou A, Ledderose J, van Diepen M, Holzhütter HG, Trimbuch T, Gimber N, Schmoranzer J, Lieberam I, Rosenmund C, Spahn C, Scheerer P, Szczepek M, Leondaritis G, Eickholt BJ

Title:The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches

Journal:Cell Rep Year:2019; Volume:29Issue:(7):Pages:2028-2040.e8. doi: 10.1016/j.celrep.2019.10.039.

Authors:Kalveram L, Kleinau G, Szymańska K, Scheerer P, Rivero-Müller A, Grüters-Kieslich A, Biebermann H

Title:The Pathogenic TSH β-subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR

Journal:Int J Mol Sci Year:2019; Volume:20Issue:(22):Pages:pii: E5564. doi: 10.3390/ijms20225564.

Authors:Heyder N, Kleinau G, Szczepek M, Kwiatkowski D, Speck D, Soletto L, Cerdá-Reverter JM, Krude H, Kühnen P, Biebermann H, Scheerer P

Title:Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective

Journal:Frontiers Endocrinol Year:2019; :Pages:10:515. doi: 10.3389/fendo.2019.00515. eCollection.

Authors:Fernandez Lopez M, Nguyen AD, Velazquez Escobar F, González R, Michael N, Nogacz Ż, Piwowarski P, Bartl F, Siebert F, Heise I, Scheerer P, Gärtner W, Mroginski MA, Hildebrandt P

Title:Role of the Propionic Side Chains for the Photoconversion of Bacterial Phytochromes

Journal:Biochemistry Year:2019; :Pages:. doi: 10.1021/acs.biochem.9b00526.

Authors:Hildebrand PW, Rose AS, Tiemann JKS

Title:Bringing Molecular Dynamics Simulation Data into View

Journal:Trends Biochem Sci Year:2019; :Pages:. pii: S0968-0004(19)30137-9. doi: 10.1016/j.tibs.2019.06.004. [Epub ahead of print] Review.

Authors:Zhao J, Zhang H, Qin B, Nikolay R, He QY, Spahn CMT, Zhang G

Title:Multifaceted Stoichiometry Control of Bacterial Operons Revealed by Deep Proteome Quantification

Journal:Frontiers Genet Year:2019; Volume:10:Pages:473. doi: 10.3389/fgene.2019.00473. eCollection 2019..

Authors:Lytvynenko I, Paternoga H, Thrun A, Balke A, Müller TA, Chiang CH, Nagler K, Tsaprailis G, Anders S, Bischofs I, Maupin-Furlow JA, Spahn CMT, Joazeiro CAP

Title:Alanine Tails Signal Proteolysis in Bacterial Ribosome-Associated Quality Control

Journal:Cell Year:2019; Volume:178Issue:(1):Pages:76-90.e22. doi: 10.1016/j.cell.2019.05.002.

Authors:Liu X, Xu X, Hilger D, Aschauer P, Tiemann JKS, Du Y, Liu H, Hirata K, Sun X, Guixà-González R, Mathiesen JM, Hildebrand PW, Kobilka BK

Title:Structural Insights into the Process of GPCR-G Protein Complex Formation

Journal:Cell Year:2019; Volume:177Issue:(5):Pages:1243-1251.e12. doi: 10.1016/j.cell.2019.04.021.

Authors:Fragel SM, Montada A, Heermann R, Baumann U, Schacherl M, Schnetz K

Title:Characterization of the pleiotropic LysR-type transcription regulator LeuO of Escherichia coli

Journal:Nucleic Acids Res Year:2019; :Pages:pii: gkz506. doi: 10.1093/nar/gkz506.

Authors:Pichlo C, Juetten L, Wojtalla F, Schacherl M, Diaz D, Baumann U

Title:Molecular determinants of the mechanism and substrate specificity of Clostridium difficile proline-proline endopeptidase-1

Journal:J Biol Chem Year:2019; Volume:294Issue:(30):Pages:11525-11535. doi: 10.1074/jbc.RA119.009029.

Authors:Mayer D, Damberger FF, Samarasimhareddy M, Feldmueller M, Vuckovic Z, Flock T, Bauer B, Mutt E, Zosel F, Allain FHT, Standfuss J, Schertler GFX, Deupi X, Sommer ME, Hurevich M, Friedler A, Veprintsev DB

Title:Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

Journal:Nat Commun Year:2019; Volume:10Issue:(1):Pages:1261. doi: 10.1038/s41467-019-09204-y..

Authors:Krupp F, Said N, Huang YH, Loll B, Bürger J, Mielke T, Spahn CMT, Wahl MC

Title:Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor

Journal:Mol Cell Year:2019; Volume:74Issue:(1):Pages:143-157.e5. doi: 10.1016/j.molcel.2019.01.016.

Authors:Zhao J, Qin B, Nikolay R, Spahn CMT, Zhang G

Title:Translatomics: The Global View of Translation

Journal:Int J Mol Sci Year:2019; Volume:20Issue:(1):Pages:pii: E212. doi: 10.3390/ijms20010212.

Authors:Heck M, Hofmann KP, Kraft TW, Lamb TD

Title:Phototransduction gain at the G-protein, transducin, and effector protein, phosphodiesterase-6, stages in retinal rods

Journal:Proc Natl Acad Sci U S A Year:2019; Volume:116Issue:(18):Pages:8653-8654.

Authors:Jacobi SF, Khajavi N, Kleinau G, Teumer A, Scheerer P, Homuth G, Völzke H, Wiegand S, Kühnen P, Krude H, Gong M, Raile K, Biebermann H

Title:Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes

Journal:Diabetes Obes Metab Year:2019; Volume:21Issue:(5):Pages:1168-1176. doi: 10.1111/dom.13634. Epub .

Authors:Buhrke D, Tavraz NN, Shcherbakova DM, Sauthof L, Moldenhauer M, Vélazquez Escobar F, Verkhusha VV, Hildebrandt P, Friedrich T

Title:Chromophore binding to two cysteines increases quantum yield of near-infrared fluorescent proteins

Journal:Sci Rep Year:2019; Volume:9Issue:(1):Pages:1866. doi: 10.1038/s41598-018-38433-2.

Authors:Biebermann H, Kleinau G, Schnabel D, Bockenhauer D, Wilson LC, Tully I, Kiff S, Scheerer P, Reyes M, Paisdzior S, Gregory JW, Allgrove J, Krude H, Mannstadt M, Gardella TJ, Dattani M, Jüppner H, Grüters A

Title:A New Multisystem Disorder Caused by the Gαs Mutation p.F376V

Journal:J Clin Endocrinol Metab Year:2019; Volume:104Issue:(4):Pages:1079-1089.