Publications of the Institute of Medical Physics and Biophysics in 2016

Authors:Hilal T, Yamamoto H, Loerke J, Bürger J, Mielke T, Spahn CM

Title:Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution

Journal:Nat Commun Year:2016; Volume:7:Pages:13521. doi: 10.1038/ncomms13521.

Authors:Müller A, Berkmann JC, Scheerer P, Biebermann H, Kleinau G

Title:Insights into Basal Signaling Regulation, Oligomerization, and Structural Organization of the Human G-Protein Coupled Receptor 83

Journal:PLoS One Year:2016; Volume:11Issue:(12):Pages::e0168260. doi: 10.1371/journal.pone.0168260. eCollection 2016.

Authors:Peterhans C, Lally CC, Ostermaier MK, Sommer ME, Standfuss J

Title:Functional map of arrestin binding to phosphorylated opsin, with and without agonist

Journal:Sci Rep Year:2016; Volume:6Issue:(28686):Pages:doi: 10.1038/srep28686.

Authors:Domagalska J, Janas A, Pyta K, Pecyna P, Ruszkowski P, Celewicz L, Gajecka M, Bartl F, Przybylski P.

Title:16-Membered Macrolide Lactone Derivatives Bearing a Triazole-Functionalized Arm at the Aglycone C13 Position as Antibacterial and Anticancer Agents

Journal:ChemMedChem Year:2016; Volume:11Issue:(17):Pages:1886-91. doi: 10.1002/cmdc.201600250. Epub 2016 Jul 14.

Authors:Huczyński A, Majcher U, Maj E, Wietrzyk J, Janczak J, Moshari M, Tuszynski JA, Bartl F

Title:Synthesis, antiproliferative activity and molecular docking of Colchicine derivatives

Journal:Bioorg Chem Year:2016; Volume:64:Pages:103-12. doi: 10.1016/j.bioorg.2016.01.002. Epub 2016 Jan 12.

Authors:Möncke-Buchner E, Szczepek M, Bokelmann M, Heinemann P, Raftery MJ, Krüger DH, Reuter M

Title:Sin Nombre hantavirus nucleocapsid protein exhibits a metal-dependent DNA-specific endonucleolytic activity

Journal:Virology Year:2016; Volume:496:Pages:67-76. doi: 10.1016/j.virol.2016.05.009. Epub 2016 Jun 1.

Authors:Buhrke D, Velazquez Escobar F, Sauthof L, Wilkening S, Herder N, Tavraz NN, Willoweit M, Keidel A, Utesch T, Mroginski MA

Title:The role of local and remote amino acid substitutions for optimizing fluorescence in bacteriophytochromes: A case study on iRFP

Journal:Sci Rep Year:2016; Volume:22Issue:(6):Pages:28444. doi: 10.1038/srep28444.

Authors:Prinz F, Puetter V, Holton SJ, Andres D, Stegmann CM, Kwiatkowski D, Prechtl S, Petersen K, Beckmann G, Kreft B, Mumberg D, Montalván AF

Title:Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells

Journal:J Biol Chem Year:2016; Volume:291Issue:(21):Pages:11252-67. doi: 10.1074/jbc.M115.702142. Epub 2016 Mar 30.

Authors:Ayaz P, Andres D, Kwiatkowski DA, Kolbe CC, Lienau P, Siemeister G, Lücking U, Stegmann CM

Title:Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9

Journal:ACS Chem Biol Year:2016; Volume:11Issue:(6):Pages:1710-9. doi: 10.1021/acschembio.6b00074. Epub 2016 Apr 19.

Authors:Qin B, Yamamoto H, Ueda T, Varshney U, Nierhaus KH

Title:The Termination Phase in Protein Synthesis is not Obligatorily Followed by the RRF/EF-G-Dependent Recycling Phase

Journal:J Mol Biol Year:2016; Volume:428Issue:(18):Pages:3577-87. doi: 10.1016/j.jmb.2016.05.019. Epub 2016 May 31.

Authors:Nikolay R, Schmidt S, Schlömer R, Deuerling E, Nierhaus KH

Title:Ribosome Assembly as Antimicrobial Target

Journal:Antibiotics Year:2016; Volume:5Issue:(2):Pages: pii: E18. doi: 10.3390/antibiotics5020018.

Authors:Yamamoto H, Wittek D, Gupta R, Qin B, Ueda T, Krause R, Yamamoto K, Albrecht R, Pech M, Nierhaus KH

Title:70S-scanning initiation is a novel and frequent initiation mode of ribosomal translation in bacteria

Journal:Proc Natl Acad Sci U S A. Year:2016; Volume:113Issue:(9):Pages:E1180-9. doi: 10.1073/pnas.1524554113. Epub 2016 Feb 17.

Authors:Wilson DN, Spahn CM

Title:Knud Hermann Nierhaus 1941-2016

Journal:Nat Struct Mol Biol Year:2016; Volume:23Issue:(6):Pages::503-4. doi: 10.1038/nsmb.3239.

Authors:Banthiya S, Kalms J, Galemou Yoga E, Ivanov I, Carpena X, Hamberg M, Kuhn H, Scheerer P

Title:Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa

Journal:Biochim Biophys Acta Year:2016; Volume:1861Issue:(11):Pages:1681-1692.

Authors:Nagano S, Scheerer P, Zubow K, Michael N, Inomata K, Lamparter T, Krauß N.

Title:The Crystal Structures of the N-terminal Photosensory Core Module of Agrobacterium Phytochrome Agp1 as Parallel and Anti-parallel Dimers

Journal:J Biol Chem Year:2016; Volume:291Issue:(39):Pages:20674-91.

Authors:Sprink T, Ramrath DJ, Yamamoto H, Yamamoto K, Loerke J, Ismer J, Hildebrand PW, Scheerer P, Bürger J, Mielke T, Spahn CM

Title:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association

Journal:Sci Adv Year:2016; Volume:2Issue:(3):Pages:e1501502. doi: 10.1126/sciadv.1501502. eCollection 2016.

Authors:Kalms J, Schmidt A, Frielingsdorf S, van der Linden P, von Stetten D, Lenz O, Carpentier P, Scheerer P.

Title:Krypton Derivatization of an O2 -Tolerant Membrane-Bound [NiFe] Hydrogenase Reveals a Hydrophobic Tunnel Network for Gas Transport

Journal:Angew Chem Int Ed Engl Year:2016; Volume:55Issue:(18):Pages:5586-90. doi: 10.1002/anie.201508976. Epub 2016 Feb 23.

Authors:Kalms J, Schmidt A, Frielingsdorf S, van der Linden P, von Stetten D, Lenz O, Carpentier P, Scheerer P

Title:Ein Netzwerk aus hydrophoben Tunneln zum Transport gasförmiger Reaktanten in einer O2-toleranten, membrangebundenen [NiFe]- Hydrogenase, aufgedeckt durch Derivatisierung mit Krypton

Journal:Angewandte Chemie Year:2016; Volume:128Issue:(18):Pages:5676–5680. doi:10.1002/ange.201508976.

Authors:Ismer J, Rose AS, Tiemann JK, Goede A, Preissner R, Hildebrand PW

Title:SL2: an interactive webtool for modeling of missing segments in proteins

Journal:Nucleic Acids Res Year:2016; Volume:44Issue:(W1):Pages:W390-4.