Publications of the Institute of Medical Physics and Biophysics

Authors:Bo Qin, Simon M. Lauer, Annika Balke, Carlos H. Vieira-Vieira, Jörg Bürger,1, Thorsten Mielke, Matthias Selbach, Patrick Scheerer, Christian M. T. Spahn, and Rainer Nikolay

Title:Cryo-EM captures early ribosome assembly in action

Journal:Nat Commun Year:2023; Volume:14Issue:(898):Pages:doi: 10.1038/s41467-023-36607-9.

Authors:Tarek Hilal, Benjamin Y Killam, Milica Grozdanović, Malgorzata Dobosz-Bartoszek, Justus Loerke, Jörg Bürger, Thorsten Mielke, Paul R Copeland, Miljan Simonović, Christian M T Spahn

Title:Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon

Journal:Science Year:2022; :Pages:DOI: 10.1126/science.abg3875.

Authors:Speck D, Kleinau G, Szczepek M, Kwiatkowski D, Catar R, Philippe A, Scheerer P

Title:Angiotensin and Endothelin Receptor Structures With Implications for Signaling Regulation and Pharmacological Targeting

Journal:Front Endocrinol (Lausanne) Year:2022; Volume:13:Pages:880002. doi: 10.3389/fendo.2022.880002. eCollection 2022.

Authors:Philippe A, Kleinau G, Gruner JJ, Wu S, Postpieszala D, Speck D, Heidecke H, Dowell SJ, Riemekasten G, Hildebrand PW, Kamhieh-Milz J, Catar R, Szczepek M, Dragun D, Scheerer P.

Title:Molecular Effects of Auto-Antibodies on Angiotensin II Type 1 Receptor Signaling and Cell Proliferation

Journal:Int J Mol Sci Year:2022; Volume:23Issue:(7):Pages:3984. doi: 10.3390/ijms23073984.

Authors:Speck D, Kleinau G, Meininghaus M, Erbe A, Einfeldt A, Szczepek M, Scheerer P, Pütter V.

Title:Expression and Characterization of Relaxin Family Peptide Receptor 1 Variants

Journal:Frontiers Pharmacol Year:2022; Volume:12Issue:(826112):Pages:doi: 10.3389/fphar.2021.826112.

Authors:Nicolas A Heyder, Gunnar Kleinau, David Speck, Andrea Schmidt, Sarah Paisdzior, Michal Szczepek, Brian Bauer, Anja Koch, Monique Gallandi, Dennis Kwiatkowski, Jörg Bürger, Thorsten Mielke, Annette G Beck-Sickinger, Peter W Hildebrand, Christian M T Spahn, Daniel Hilger, Magdalena Schacherl, Heike Biebermann, Tarek Hilal, Peter Kühnen, Brian K Kobilka, Patrick Scheerer

Title:Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide

Journal:Cell Research Year:2021; Volume:PMID: 34561620 DOI: 10.1038/s41422-021-00569-8

Authors:Rainer Nikolay, Tarek Hilal, Sabine Schmidt, Bo Qin, David Schwefel, Carlos H Vieira-Vieira, Thorsten Mielke , Jörg Bürger, Justus Loerke, Kazuaki Amikura, Timo Flügel, Takuya Ueda, Matthias Selbach, Elke Deuerling, Christian M T Spahn

Title:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization

Journal:Mol Cell Year:2021; :Pages:DOI: 10.1016/j.molcel.2021.02.006.

Authors:Gerti Beliu, Steffen Altrichter, Ramon Guixà-González, Mareike Hemberger, Ina Brauer, Anne-Kristin Dahse, Nicole Scholz, Robert Wieduwild, Alexander Kuhlemann, Hossein Batebi, Florian Seufert, Guillermo Pérez-Hernández, Peter W Hildebrand, Markus Sauer, Tobias Langenhan

Title:Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain

Journal:Mol Cell Year:2021; Volume:DOI: 10.1016/j.molcel.2020.12.042