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Prof. Dr. Christian Spahn

Director and Group leader

Charité – Universitätsmedizin Berlin Institute of Medical Physics and Biophysics
Charitéplatz 1
10117 Berlin

Campus / internal address:
CharitéCrossOver, Virchowweg 6

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Expertise

  1. Cryo-electron microscopy (cryo-EM) in combination with digital image processing (single particle approach) to determine the structure of large macromolecular assemblies and machines
  2. Structure and function of macromolecular machines
  3. Mechanism of protein biosynthesis and translational control

Vita Prof. Dr. Christian Spahn

Academic education

1991 - 1996

Doctoral studies (Dr. rer. nat.) in Biochemistry, Freie Universität Berlin

1986 - 1991

Studies (Diploma) in Biochemistry, Freie Universität Berlin

 

Academic degrees

1996

Dr. rer. nat., Biochemistry, Freie Universität Berlin, advisor: Prof. Dr. K. H. Nierhaus (MPI für Molekulare Genetik)

1991

Diploma, Biochemistry, Freie Universität Berlin, Prof. Dr. K. H. Nierhaus (MPI für Molekulare Genetik)

 

 

Professional career

2009 - present

Head of the Institut für Medizinische Physik und Biophysik, Charité - Universitätsmedizin Berlin

2007 - present

Professor (W3) for Biophysics, Charité - Universitätsmedizin Berlin

2007

Offer of a research professorship (W3) for “Cryo-Elektronenmikroscopie” in the framework of the Cluster of Excellence “Cellular Network”, Ruprecht-Karls-Universität Heidelberg, offer declined

2007

Offer of a professorship (W3) for “Electron Cryo-Microscopy of Large Macromolecular Complexes” in the framework of the Cluster of Excellence “Macromolecular Complexes”, Johann Wolfgang Goethe-Universität Frankfurt (Main), offer declined

2006 - 2007

Professor (W2) for Biophysics, Charité - Universitätsmedizin Berlin

2002 - 2007

Young independent research group leader (VolkswagenStiftung): “Signalstrukturen der mRNA und ihre Interaktionen mit dem Translationsapparat - Kryo-Elektronenmikroskopie makro-molekularer Maschinen“

2002 - 2006

Junior professorship, Charité - Universitätsmedizin Berlin

2002

Offer of a assistant professorship, Columbia University, New York, and the position of a head of cryo-electron microsopy, New Yok Structural Biology Center, offer declined

1998 - 2002

Research assistant, Howard Hughes Medical Institute / Health Research Inc., group of Prof. Joachim Frank

1996 - 1998

Research assistant, MPI für Molekulare Genetik, group of Prof. Dr. K. H. Nierhaus

 

 

Fellowships and awards

2016

Elected Member of the Leopoldina

2014

Elected Member of EMBO

2004

EMBO Young Investigator Award (2005-2007)

 

 

Activities in the scientific community (since 2006)

2018

 

2014

Co-Organizer international symposium "Membranes and Modules" (together with W. Nickel und S. Sigrist)

Co-Organizer international symposium “Membranes and Modules” (together with S. Sigrist and Z. Ignatova)

2012 - 2016

Principal investigator of a Human Frontier Science Programme-funded research group “From the end to the beginning: termination and ribosome recycling in eukaryotic translation”

2012 - present

Vice-speaker of the DFG-research unit FOR 1805

2012

Chair of the Gordon Research Conference “Three Dimensional Electron Microscopy”

2011 - present

Speaker of the CRC 740 “From Molecules to Modules”

2011

Vice-chair of the Gordon Research Conference “Three Dimensional Electron Microscopy”

2009

Co-Organizer international symposium "Membranes and Modules" (together with V. Haucke)

2007 - 2010

Co-founder and vice-speaker of the CRC 740 “From Molecules to Modules”

2006

Chairman CSHL Translational Control Meeting



Links

Group leader of the workgroup Cryo-electron microscopy of macromolecular machines

Publications

SFB 958

FOR 1805

SFB 1423

Core Facility for Cryo-Electron Microscopy

Exzellenzcluster NeuroCure

Ultrastrukturnetzwerk



Research profile


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